It often acts rapidly-typically within a couple of hours-to relieve depression symptoms. Esketamine is delivered as a nasal spray in a health care provider’s office, a clinic, or a hospital. ![]() People who are sensitive to the side effects of these medications sometimes benefit from starting with a low dose, increasing the daily dose very slowly, and adjusting when they take the medication (for example, at bedtime or with food).Įsketamine is a newer FDA-approved medication for treatment-resistant depression, which may be diagnosed when a person’s symptoms have not improved after trying at least two antidepressant therapies. ![]() The side effects are generally mild and tend to improve over time. It is important for people to follow their health care provider’s directions and take the medication for the recommended amount of time before deciding whether it works.Ĭommon side effects of SSRIs and other antidepressants may include upset stomach, headache, or sexual dysfunction. Although older antidepressant medications, such as tricyclics and monoamine oxidase inhibitors (MAOIs), are associated with more side effects, they may be the best option for some people.Īntidepressant medications take time to work-usually 4 to 8 weeks-and symptoms such as problems with sleep, appetite, energy, or concentration sometimes improve before mood lifts. These medications are commonly prescribed because they improve symptoms related to a broad group of depressive and anxiety disorders and are associated with fewer side effects than older types of antidepressants. In some cases, health care providers may prescribe antidepressants to treat other health conditions such as anxiety, pain, and insomnia.Ĭommonly prescribed types of antidepressants include selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), and norepinephrine-dopamine reuptake inhibitors (NDRIs). AntidepressantsĪntidepressants are medications used to treat depression. This page provides basic information about mental health medications, but it is not a complete source for all medications available and should not be used as a guide for making medical decisions. The MedlinePlus Drugs, Herbs and Supplements website also provides information on medications, including side effects and FDA warnings. Food and Drug Administration (FDA) Medication Guides webpage for the latest warnings, patient medication guides, and newly approved medications. Information about medications is updated frequently. It’s important for people to work with a health care provider or mental health professional to develop a treatment plan that meets their needs and medical situation. Medications can affect people in different ways, and it may take several tries to find the medication that is most effective with the fewest side effects. Medications can play a role in treating mental disorders and conditions and are often used in combination with other treatment approaches such as psychotherapies and brain stimulation therapies. Research Training and Career Development Opportunities.Research Conducted at NIMH (Intramural Research Program).Upcoming Observances and Related Events.Contribute to Mental Health Research Mobile navigation
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